Antigenic diversity in Theileria parva in vaccine stabilate and African buffalo
نویسنده
چکیده
........................................................................................................................ i Acknowledgement ......................................................................................................iii Table of contents ......................................................................................................... iv List of figures ............................................................................................................... x List of tables.............................................................................................................. xiv Abbreviations.................................................................................xvii Chapter 1: General introduction................................................................................... 1 1.1 Theileria parva................................................................................................... 1 1.1.1 Life-cycle .................................................................................................... 1 1.1.2 Clinical signs and nomenclature ................................................................. 4 1.1.3 Diagnosis..................................................................................................... 5 1.1.4 Control of T. parva...................................................................................... 6 1.2 The Muguga cocktail ......................................................................................... 8 1.2.
منابع مشابه
Ancient diversity and geographical sub-structuring in African buffalo Theileria parva populations revealed through metagenetic analysis of antigen-encoding loci☆
An infection and treatment protocol involving infection with a mixture of three parasite isolates and simultaneous treatment with oxytetracycline is currently used to vaccinate cattle against Theileria parva. While vaccination results in high levels of protection in some regions, little or no protection is observed in areas where animals are challenged predominantly by parasites of buffalo orig...
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An infection and treatment protocol is used to vaccinate cattle against Theileria parva infection. Due to incomplete cross-protection between different parasite isolates, a mixture of three isolates, termed the Muguga cocktail, is used for vaccination. While vaccination of cattle in some regions provides high levels of protection, some animals are not protected against challenge with buffalo-de...
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Immunity to Theileria parva infection in cattle is often parasite stock specific. The antigenic diversity which is expressed at the schizont stage of the parasite together with a wild reservoir of the organism in buffalo has complicated the development of effective disease control by immunization. We have previously shown that about 70% of cattle inoculated with recombinant forms of p67, a spor...
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Theileria parva is the causative agent of Corridor disease in cattle in South Africa. The African buffalo (Syncerus caffer) is the reservoir host, and, as these animals are important for eco-tourism in South Africa, it is compulsory to test and certify them disease free prior to translocation. A T. parva-specific real-time polymerase chain reaction (PCR) test based on the small subunit ribosoma...
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East Coast fever caused by Theileria parva parva has been eradicated from South Africa, but tick-borne infections with other species of Theileria still occur, particularly in cattle and African buffalo (Syncerus caffer). One such infection is Corridor disease caused by T. parva lawrencei, which is controlled by restricting the movement of African buffalo. Other species reviewed are T. parva bov...
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